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Design Strategies, Structures and Molecular Interactions of Small Molecule Src Inhibitors.

Anti-cancer agents in medicinal chemistry

Olgen S.
PMID: 26902603
Anticancer Agents Med Chem. 2016;16(8):992-1002. doi: 10.2174/1871520616666160223111800.

In recent years, several small molecules approved by FDA for clinical studies are promising anti-cancer agent. Among the kinases, Abelson Leukaemia (Abl), sarcoma (Src), epidermal growth factor receptor (EGFR) and vascular endotelhial growth factor receptor (VEGFR) are considered as...

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Olgen S. Design Strategies, Structures and Molecular Interactions of Small Molecule Src Inhibitors. Anticancer Agents Med Chem. 2016;16(8):992-1002doi: 10.2174/1871520616666160223111800.
Olgen, S. (2016). Design Strategies, Structures and Molecular Interactions of Small Molecule Src Inhibitors. Anti-cancer agents in medicinal chemistry, 16(8), 992-1002. https://doi.org/10.2174/1871520616666160223111800
Olgen, Sureyya. "Design Strategies, Structures and Molecular Interactions of Small Molecule Src Inhibitors." Anti-cancer agents in medicinal chemistry vol. 16,8 (2016): 992-1002. doi: https://doi.org/10.2174/1871520616666160223111800
Olgen S. Design Strategies, Structures and Molecular Interactions of Small Molecule Src Inhibitors. Anticancer Agents Med Chem. 2016;16(8):992-1002. doi: 10.2174/1871520616666160223111800. PMID: 26902603.
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New Pyrano[2,3-d:6,5-d']dipyrimidine Derivatives-Synthesis, in vitro Cytotoxicity and Computational Studies.

Anti-cancer agents in medicinal chemistry

Maddila S, Naicker K, Gorle S, Rana S, Yalagala K, Maddila SN, Singh M, Singh P, Jonnalagadda SB.
PMID: 26592746
Anticancer Agents Med Chem. 2016;16(8):1031-1037. doi: 10.2174/1871520616666151123095932.

A new series of pyrano[2,3-d:6,5-d']dipyrimidine derivatives were synthesized and evaluated for their in vitro anticancer activity. The structures of all the synthesized compounds were confirmed by 1H NMR, 13C NMR, 15N NMR, HR-MS and FT-IR spectral analyses. The cytotoxic...

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Maddila S, Naicker K, Gorle S, et al. New Pyrano[2,3-d:6,5-d']dipyrimidine Derivatives-Synthesis, in vitro Cytotoxicity and Computational Studies. Anticancer Agents Med Chem. 2016;16(8):1031-1037doi: 10.2174/1871520616666151123095932.
Maddila, S., Naicker, K., Gorle, S., Rana, S., Yalagala, K., Maddila, S. N., Singh, M., Singh, P., & Jonnalagadda, S. B. (2016). New Pyrano[2,3-d:6,5-d']dipyrimidine Derivatives-Synthesis, in vitro Cytotoxicity and Computational Studies. Anti-cancer agents in medicinal chemistry, 16(8), 1031-1037. https://doi.org/10.2174/1871520616666151123095932
Maddila, Suresh, et al. "New Pyrano[2,3-d:6,5-d']dipyrimidine Derivatives-Synthesis, in vitro Cytotoxicity and Computational Studies." Anti-cancer agents in medicinal chemistry vol. 16,8 (2016): 1031-1037. doi: https://doi.org/10.2174/1871520616666151123095932
Maddila S, Naicker K, Gorle S, Rana S, Yalagala K, Maddila SN, Singh M, Singh P, Jonnalagadda SB. New Pyrano[2,3-d:6,5-d']dipyrimidine Derivatives-Synthesis, in vitro Cytotoxicity and Computational Studies. Anticancer Agents Med Chem. 2016;16(8):1031-1037. doi: 10.2174/1871520616666151123095932. PMID: 26592746.
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Plant-Derived Secondary Metabolites as Anticancer Agents.

Anti-cancer agents in medicinal chemistry

Rawat DS, Singh R.
PMID: 23438829
Anticancer Agents Med Chem. 2013 Feb 07; Epub 2013 Feb 07.

No abstract available.

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Rawat DS, Singh R. Plant-Derived Secondary Metabolites as Anticancer Agents. Anticancer Agents Med Chem. 2013;
Rawat, D. S., & Singh, R. (2013). Plant-Derived Secondary Metabolites as Anticancer Agents. Anti-cancer agents in medicinal chemistry, .
Rawat, Diwan S, and Singh, Ram. "Plant-Derived Secondary Metabolites as Anticancer Agents." Anti-cancer agents in medicinal chemistry vol. (2013).
Rawat DS, Singh R. Plant-Derived Secondary Metabolites as Anticancer Agents. Anticancer Agents Med Chem. 2013 Feb 07; Epub 2013 Feb 07. PMID: 23438829.
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RETRACTED: Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate.

Anti-cancer agents in medicinal chemistry

Lu DY, Lu TR, Xu B.
PMID: 30205804
Anticancer Agents Med Chem. 2018;18(14):1952-1961. doi: 10.2174/1871520618666180911113141.

The article entitled “Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate”, by Lu D.Y., Lu T.R., Xu B., Varki A., Huang M., Zhu H., Shen Y., Yarla N.S., has been retracted on the request of...

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Lu DY, Lu TR, Xu B. RETRACTED: Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate. Anticancer Agents Med Chem. 2018;18(14):1952-1961doi: 10.2174/1871520618666180911113141.
Lu, D. Y., Lu, T. R., & Xu, B. (2018). RETRACTED: Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate. Anti-cancer agents in medicinal chemistry, 18(14), 1952-1961. https://doi.org/10.2174/1871520618666180911113141
Lu, D Y, et al. "RETRACTED: Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate." Anti-cancer agents in medicinal chemistry vol. 18,14 (2018): 1952-1961. doi: https://doi.org/10.2174/1871520618666180911113141
Lu DY, Lu TR, Xu B. RETRACTED: Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate. Anticancer Agents Med Chem. 2018;18(14):1952-1961. doi: 10.2174/1871520618666180911113141. PMID: 30205804.
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Rotundic Acid Regulates the Effects of Let-7f-5p on Caco2 Cell Proliferation.

Anti-cancer agents in medicinal chemistry

Feng Y, Liu X, Han Y, Chen M, Zhang L, Hu Y, Chen L, Chen G, Li N.
PMID: 32748760
Anticancer Agents Med Chem. 2021;21(7):902-909. doi: 10.2174/1871520620999200730165829.

BACKGROUND & OBJECTIVE: Nowadays, the interaction between natural products and microRNAs provides a promising field for exploring the chemopreventive agents for various cancers. As a member of microRNAs, the expression of let-7f-5p is universally downregulated in Colorectal Cancer (CRC)....

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Feng Y, Liu X, Han Y, et al. Rotundic Acid Regulates the Effects of Let-7f-5p on Caco2 Cell Proliferation. Anticancer Agents Med Chem. 2021;21(7):902-909doi: 10.2174/1871520620999200730165829.
Feng, Y., Liu, X., Han, Y., Chen, M., Zhang, L., Hu, Y., Chen, L., Chen, G., & Li, N. (2021). Rotundic Acid Regulates the Effects of Let-7f-5p on Caco2 Cell Proliferation. Anti-cancer agents in medicinal chemistry, 21(7), 902-909. https://doi.org/10.2174/1871520620999200730165829
Feng, Yuan, et al. "Rotundic Acid Regulates the Effects of Let-7f-5p on Caco2 Cell Proliferation." Anti-cancer agents in medicinal chemistry vol. 21,7 (2021): 902-909. doi: https://doi.org/10.2174/1871520620999200730165829
Feng Y, Liu X, Han Y, Chen M, Zhang L, Hu Y, Chen L, Chen G, Li N. Rotundic Acid Regulates the Effects of Let-7f-5p on Caco2 Cell Proliferation. Anticancer Agents Med Chem. 2021;21(7):902-909. doi: 10.2174/1871520620999200730165829. PMID: 32748760.
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On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7).

Anti-cancer agents in medicinal chemistry

Leite CM, de Araujo-Neto JH, Corrêa RS, Colina-Vegas L, Martínez-Otero D, Martins PR, Silva CG, Batista AA.
PMID: 32838726
Anticancer Agents Med Chem. 2021;21(9):1172-1182. doi: 10.2174/1871520620666200824114816.

BACKGROUND: Breast cancer is one of the most common types among women. Its incidence progressively increases with age, especially after age 50. Platinum compounds are not efficient in the treatment of breast cancer, highlighting the use of other metals...

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Leite CM, de Araujo-Neto JH, Corrêa RS, et al. On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7). Anticancer Agents Med Chem. 2021;21(9):1172-1182doi: 10.2174/1871520620666200824114816.
Leite, C. M., de Araujo-Neto, J. H., Corrêa, R. S., Colina-Vegas, L., Martínez-Otero, D., Martins, P. R., Silva, C. G., & Batista, A. A. (2021). On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7). Anti-cancer agents in medicinal chemistry, 21(9), 1172-1182. https://doi.org/10.2174/1871520620666200824114816
Leite, Celisnolia M, et al. "On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7)." Anti-cancer agents in medicinal chemistry vol. 21,9 (2021): 1172-1182. doi: https://doi.org/10.2174/1871520620666200824114816
Leite CM, de Araujo-Neto JH, Corrêa RS, Colina-Vegas L, Martínez-Otero D, Martins PR, Silva CG, Batista AA. On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7). Anticancer Agents Med Chem. 2021;21(9):1172-1182. doi: 10.2174/1871520620666200824114816. PMID: 32838726.
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OVERVIEW.

Anti-cancer agents in medicinal chemistry

Prudhomme M.
PMID: 31204619
Anticancer Agents Med Chem. 2019;19(1):2. doi: 10.2174/187152061901190321114512.

No abstract available.

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Prudhomme M. OVERVIEW. Anticancer Agents Med Chem. 2019;19(1):2doi: 10.2174/187152061901190321114512.
Prudhomme, M. (2019). OVERVIEW. Anti-cancer agents in medicinal chemistry, 19(1), 2. https://doi.org/10.2174/187152061901190321114512
Prudhomme, Michelle. "OVERVIEW." Anti-cancer agents in medicinal chemistry vol. 19,1 (2019): 2. doi: https://doi.org/10.2174/187152061901190321114512
Prudhomme M. OVERVIEW. Anticancer Agents Med Chem. 2019;19(1):2. doi: 10.2174/187152061901190321114512. PMID: 31204619.
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iRGD Co-Administration with Paclitaxel-Loaded PLGA Nanoparticles Enhance Targeting and Antitumor Effect in Colorectal Cancer Treatment.

Anti-cancer agents in medicinal chemistry

Li L, Yang M, Li R, Hu J, Yu L, Qian X.
PMID: 32698755
Anticancer Agents Med Chem. 2021;21(7):910-918. doi: 10.2174/1871520620666200721134919.

OBJECTIVE: To explore the targeting effect of PLGA-NP and iRGD co-administration with PTXPLGA NP (PTX-PLGA + iRGD) on colorectal cancer.METHODS: Whether PLGA-NP co-administration with iRGD peptide could show effective tumor-targeting ability in contrast to with PLGA-NP in colorectal cancer...

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Li L, Yang M, Li R, et al. iRGD Co-Administration with Paclitaxel-Loaded PLGA Nanoparticles Enhance Targeting and Antitumor Effect in Colorectal Cancer Treatment. Anticancer Agents Med Chem. 2021;21(7):910-918doi: 10.2174/1871520620666200721134919.
Li, L., Yang, M., Li, R., Hu, J., Yu, L., & Qian, X. (2021). iRGD Co-Administration with Paclitaxel-Loaded PLGA Nanoparticles Enhance Targeting and Antitumor Effect in Colorectal Cancer Treatment. Anti-cancer agents in medicinal chemistry, 21(7), 910-918. https://doi.org/10.2174/1871520620666200721134919
Li, Li, et al. "iRGD Co-Administration with Paclitaxel-Loaded PLGA Nanoparticles Enhance Targeting and Antitumor Effect in Colorectal Cancer Treatment." Anti-cancer agents in medicinal chemistry vol. 21,7 (2021): 910-918. doi: https://doi.org/10.2174/1871520620666200721134919
Li L, Yang M, Li R, Hu J, Yu L, Qian X. iRGD Co-Administration with Paclitaxel-Loaded PLGA Nanoparticles Enhance Targeting and Antitumor Effect in Colorectal Cancer Treatment. Anticancer Agents Med Chem. 2021;21(7):910-918. doi: 10.2174/1871520620666200721134919. PMID: 32698755.
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Withdrawn: A brief review of scaffold/ drug repurposing for breast cancer therapy.

Anti-cancer agents in medicinal chemistry

Jubie S, Yadav N.
PMID: 30864511
Anticancer Agents Med Chem. 2019 Mar 12; doi: 10.2174/1389557519666190312124142. Epub 2019 Mar 12.

No abstract available.

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Jubie S, Yadav N. Withdrawn: A brief review of scaffold/ drug repurposing for breast cancer therapy. Anticancer Agents Med Chem. 2019;doi: 10.2174/1389557519666190312124142.
Jubie, S., & Yadav, N. (2019). Withdrawn: A brief review of scaffold/ drug repurposing for breast cancer therapy. Anti-cancer agents in medicinal chemistry, . https://doi.org/10.2174/1389557519666190312124142
Jubie, Selvaraj, and Yadav, Neetu. "Withdrawn: A brief review of scaffold/ drug repurposing for breast cancer therapy." Anti-cancer agents in medicinal chemistry vol. (2019). doi: https://doi.org/10.2174/1389557519666190312124142
Jubie S, Yadav N. Withdrawn: A brief review of scaffold/ drug repurposing for breast cancer therapy. Anticancer Agents Med Chem. 2019 Mar 12; doi: 10.2174/1389557519666190312124142. Epub 2019 Mar 12. PMID: 30864511.
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Study of the Parameters Affecting the Loading of Fluorescein on Coated Gold Nanoparticles: Promising Nanostructure for Cancer Diagnosis.

Anti-cancer agents in medicinal chemistry

Hendi N, Shakeri-Zadeh A, Attaran N, Alamzadeh Z, Asefnejad A.
PMID: 33342419
Anticancer Agents Med Chem. 2021;21(17):2429-2442. doi: 10.2174/1871520621666201218114617.

BACKGROUND: Recent advances in nanotechnology have led to the use of nanomaterials in the diagnosis of cancer by imaging techniques.OBJECTIVE: This study aimed to synthesize fluorescein-conjugated gold nanoparticles and study the parameters affecting the loading of fluorescein on synthesized...

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Hendi N, Shakeri-Zadeh A, Attaran N, et al. Study of the Parameters Affecting the Loading of Fluorescein on Coated Gold Nanoparticles: Promising Nanostructure for Cancer Diagnosis. Anticancer Agents Med Chem. 2021;21(17):2429-2442doi: 10.2174/1871520621666201218114617.
Hendi, N., Shakeri-Zadeh, A., Attaran, N., Alamzadeh, Z., & Asefnejad, A. (2021). Study of the Parameters Affecting the Loading of Fluorescein on Coated Gold Nanoparticles: Promising Nanostructure for Cancer Diagnosis. Anti-cancer agents in medicinal chemistry, 21(17), 2429-2442. https://doi.org/10.2174/1871520621666201218114617
Hendi, Nazanin, et al. "Study of the Parameters Affecting the Loading of Fluorescein on Coated Gold Nanoparticles: Promising Nanostructure for Cancer Diagnosis." Anti-cancer agents in medicinal chemistry vol. 21,17 (2021): 2429-2442. doi: https://doi.org/10.2174/1871520621666201218114617
Hendi N, Shakeri-Zadeh A, Attaran N, Alamzadeh Z, Asefnejad A. Study of the Parameters Affecting the Loading of Fluorescein on Coated Gold Nanoparticles: Promising Nanostructure for Cancer Diagnosis. Anticancer Agents Med Chem. 2021;21(17):2429-2442. doi: 10.2174/1871520621666201218114617. PMID: 33342419.
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Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells.

Anti-cancer agents in medicinal chemistry

Gomes LF, Longhi PJH, Machado L, da Cruz IBM, Montano MAE, Martins M, Machado SA, Steffani JA, Cadoná FC.
PMID: 33438563
Anticancer Agents Med Chem. 2021;21(17):2337-2350. doi: 10.2174/1871520621666210112111711.

BACKGROUND: Prostate cancer is the most common visceral neoplasia in men and frequently presents chemotherapy resistance. In this context, lemongrass (Cymbopogon citratus (D.C.) Stapf) has been studied since it presents many important biological activities, such as anticancer.OBJECTIVE: We investigated...

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Gomes LF, Longhi PJH, Machado L, et al. Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells. Anticancer Agents Med Chem. 2021;21(17):2337-2350doi: 10.2174/1871520621666210112111711.
Gomes, L. F., Longhi, P. J. H., Machado, L., da Cruz, I. B. M., Montano, M. A. E., Martins, M., Machado, S. A., Steffani, J. A., & Cadoná, F. C. (2021). Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells. Anti-cancer agents in medicinal chemistry, 21(17), 2337-2350. https://doi.org/10.2174/1871520621666210112111711
Gomes, Lucas F, et al. "Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells." Anti-cancer agents in medicinal chemistry vol. 21,17 (2021): 2337-2350. doi: https://doi.org/10.2174/1871520621666210112111711
Gomes LF, Longhi PJH, Machado L, da Cruz IBM, Montano MAE, Martins M, Machado SA, Steffani JA, Cadoná FC. Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells. Anticancer Agents Med Chem. 2021;21(17):2337-2350. doi: 10.2174/1871520621666210112111711. PMID: 33438563.
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Efficacy of Neoadjuvant Therapy in Improving Long-Term Survival of Patients with Resectable Rectal Cancer: A Meta-Analysis.

Anti-cancer agents in medicinal chemistry

Li X, Li X, Fu R, Ng D, Yang T, Zhang Y, Zhang M, Shi Y, Gu Y, Lv C, Chen G.
PMID: 34315397
Anticancer Agents Med Chem. 2021 Jul 26; doi: 10.2174/1871520621666210726134809. Epub 2021 Jul 26.

BACKGROUND: The impact of neoadjuvant therapy on long-term prognosis of patients with resectable rectal cancer is currently unknown.OBJECTIVE: This study aimed to explore the long-term prognosis of patients with resectable rectal cancer following treatment with neoadjuvant therapy.METHODS: Four major...

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Li X, Li X, Fu R, et al. Efficacy of Neoadjuvant Therapy in Improving Long-Term Survival of Patients with Resectable Rectal Cancer: A Meta-Analysis. Anticancer Agents Med Chem. 2021;doi: 10.2174/1871520621666210726134809.
Li, X., Li, X., Fu, R., Ng, D., Yang, T., Zhang, Y., Zhang, M., Shi, Y., Gu, Y., Lv, C., & Chen, G. (2021). Efficacy of Neoadjuvant Therapy in Improving Long-Term Survival of Patients with Resectable Rectal Cancer: A Meta-Analysis. Anti-cancer agents in medicinal chemistry, . https://doi.org/10.2174/1871520621666210726134809
Li, Xinlong, et al. "Efficacy of Neoadjuvant Therapy in Improving Long-Term Survival of Patients with Resectable Rectal Cancer: A Meta-Analysis." Anti-cancer agents in medicinal chemistry vol. (2021). doi: https://doi.org/10.2174/1871520621666210726134809
Li X, Li X, Fu R, Ng D, Yang T, Zhang Y, Zhang M, Shi Y, Gu Y, Lv C, Chen G. Efficacy of Neoadjuvant Therapy in Improving Long-Term Survival of Patients with Resectable Rectal Cancer: A Meta-Analysis. Anticancer Agents Med Chem. 2021 Jul 26; doi: 10.2174/1871520621666210726134809. Epub 2021 Jul 26. PMID: 34315397.
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Showing 1 to 12 of 519 entries